ageing

code of the paper "Reliability modeling and statistical analysis of accelerated degradation process with memory effects and unit-to-unit variability" fractional Brownian motion, random effects, wiener process, stochastic, expectation maximization, EM algorithm, parameter estimation, FBM, uncertainty quantification, assessment, non-Markovian

Data, calculations and text relating to my book, Ageless: The new science of getting older without getting old

⏳ Online graphical interface to explore age-related gene expression alterations in 49 GTEx human tissues

Health economic evaluation for oncogeriatrics

The source of my web site

A curated list of awesome resources for lifespan extension.

Code for the manuscript "Splicing accuracy varies across human introns, tissues and age".

Actif ageing is a portal based on the WHO framework which utilizes the three key policy proposals of Health, Participation and Security to promote active ageing. This portal makes a way for physical and mental well being, civic and social participation, safety and security including diversity and inclusion at workplaces.

Effects of ageing/declining populations on national-level indices of wealth and wellbeing

An R package using TMB to estimate growth parameters using age-at-length fisheries data, taking into account ageing error, length-bin sampling, and gear selectivity. Growth models can be specified / parameterised by the user.

Capstone project for the Google Data Analytics Certificate. Focused on social inclusion, physical health, and mental wellbeing in ageing Europeans using easySHARE data. Includes full R Markdown workflow, regression diagnostics, and visualization outputs.

This repository contains data, scripts and models for estimating and predicting intrinsic capacity (IC) based on the ICOPE framework, using longitudinal data, mixed-effects models and a multi-task deep learning modeling approach.

Code for DNA methylation extraction, age-related CpG site identification, data manipulation, genomic annotation, statistical analyses and plots include in submitted paper on sex chromosome-mediated aging methylomes in female heterogametic species

DigiMoca is an Alexa skill that launch the T-MoCA (Montreal cognitive assessment, telephone version). Digi-MoCA was designed to perform cognitive assessment by means of a conversation or dialog that is intentionally conceived as a cognitive demanding task. Therefore the resulting measure is related to the user’s level of cognitive impairment.

Verzeo's Major Project - Signs of Ageing

Causally-anchored multi-omic deep learning that recovers exercise-responsive and ageing-causal genes from human physical activity. LD-aware multi-omic Mendelian randomisation + graph-attention network, with cis-MR/colocalisation validation identifying CTSF for exceptional longevity.

Effects of tissue-specific smoothing approaches on statistical analysis in quantitative MRI

snRNA-seq2 and epigenetic ageing prediction